P9120-88

PRP8 Pre-mRNA Processing Factor 8 Homolog (PRPF8, PRP8, hPRP8, PRPC8, RP13)

Size

£448.00

SKU:: P9120-88
Purity:: Purified by Protein G affinity chromatography from hybridoma culture supernatant
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Partial recombinant sequence from human PRP8 Pre-mRNA Processing Factor 8 Homolog.
Clone:: 8C277
Format:: Supplied as a liquid in PBS, pH 7.4, 1% BSA, 0.05% sodium azide.
Extra Details:: Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa. Applications: Suitable for use in Western Blot, Dot Blot, Immunocytochemistry and Flow Cytometry. Other applications not tested. Recommended Dilution: Western Blot: 0.2-2ug/ml Immunocytochemistry: 2-100ug/ml Flow Cytometry: 0.5-2ug/sample Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.