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P9109-40R1

Protein Tyrosine Phosphatase, Receptor Type R Isoforms (PTPBR7, PTP-SL and PTPPBS gamma)

Size

£1,343.00

SKU:
P9109-40R1
Purity:
Purified
Storage Conditions:
-20°C
Supplier:
United States Biological
Host:
Mouse
Immunogen:
Recombinant protein corresponding to mouse PTP-SL-GST (NCBI accession number BN000437, expression vector pGEX-2T), expressed in E. coli.
Clone:
6A6
Format:
Supplied as a lyophilized powder from 10mM ammonium bicarbonate buffer. Reconstitute with 100mM Tris-HCl, pH 8.0, 0.05% sodium azide to 0.5mg/ml. When reconstituted to 0.5mg/ml, the BSA concentration will be 1%.
Extra Details:
Protein tyrosine phosphatases (PTPs) are the enzymes that are instrumental in determining the spatial and temporal balance between the tyrosine phosphorylated and non-phosphorylated targets, and thus coordinately regulate these cellular responses to extracellular cues. The Ptprr gene gives rise to 4 different neuronal phosphatases which differ in length of their N-terminal part and subcellular localization. PTPBR7 (72kD) is receptor-like, PTP-SL (60kD) is membrane associated and PTPPBS gamma (42 and 37kD) is a cytosolic phosphatase. This antibody is directed to the common part of these proteins. Applications: Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Shipping Conditions:
Blue Ice