P9107-48
PPP2R4 (Serine/Threonine-protein Phosphatase 2A Activator, PP2A, Subunit B', PR53 Isoform, Phosphotyrosyl Phosphatase Activator, PTPA, Serine/Threonine-protein Phosphatase 2A Regulatory Subunit 4, Serine/Threonine-protein Phosphatase 2A Regulatory Subunit B', PTPA)

Size
£760.00
- SKU:
- P9107-48
- Application:
- WB
- Purity:
- Purified.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- PPP2R4 (NP_066954.2, 1-323aa) full-length human protein.
- Format:
- Supplied as a liquid in PBS, pH 7.2.
- Extra Details:
- Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice
