P9107-34W

PDP1 (Pyruvate Dehyrogenase Phosphatase Catalytic Subunit 1, PDH, PDP, PDP 1, PDPC, PDPC 1, PPM2C, Protein phosphatase 2C)

Size

£736.00

SKU:: P9107-34W
Application:: WB
Purity:: Purified by ammonium sulfate precipitation.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to human Protein Phosphatase 2 C alpha/beta (KLH). Species Sequence homology: mouse and bovine.
Format:: Supplied as a liquid in PBS, 0.08% sodium azide.
Extra Details:: PP-2 C alpha/beta is heterodimer located in the mitochondrial matrix. Within the pyruvate dehydrogenase complex, PP-2 C alpha/beta serves to catalyze the dephosphorylation and concomitant reactivation of the E1 component’s alpha subunit. Mutations occurring in the PDP1 gene are the cause of a disease known as pyruvate dehydrogenase deficiency (PDP deficiency), which leads to neurological dysfunction from lactic acidosis. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 1:500 detected PP-2 C alpha/beta on 10ug of L6 lysates. Optimal dilutions to be determined by the researcher. Positive Control: L6 Cell Lysate. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.