P9102-27
Protein C (Coagulation Factor XIV)
Size
£787.00
- SKU:
- P9102-27
- Purity:
- Purified by Protein G affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- NS0-derived recombinant human Coagulation Factor XIV (aa43-461).
- Clone:
- 7H185
- Format:
- Supplied as a lyophilized powder from a 0.2um filtered solution in PBS, 5% trehalose. Reconstitute with 1ml sterile PBS.
- Extra Details:
- Coagulation factor XIV, also known as Protein C, has anti-coagulation activity by degrading factors VIIIa and Va, which are required for thrombin activation. Protein C deficiency results in hereditary thrombophilia, and a severe recessive form may result in massive thrombosis fatal to patient. The deduced amino acid sequence of human protein C predicts a signal peptide (aa 1-32), a propeptide (aa 33-42), and a mature chain (aa 43-461), which can be converted into two disulfide-linked chains (light: aa 43- 199 and heavy: aa 200-461). The amino acid sequence of human protein C is 99.8%, 80%, 70%, 69% and 54% identical to that of chimpanzee, canine, rat, mouse and chicken. Applications: Suitable for use in Western Blot, Immunopreciptiation and ELISA. Other applications not tested. Recommended Dilution: Western Blot: 1-2ug/ml Immunopreciptiation: 25ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice