P9075-75A

PSME1 (Proteasome Activator Complex Subunit 1, 11S Regulator Complex Subunit alpha, REG-alpha, Activator of Multicatalytic Protease Subunit 1, Interferon gamma Up-regulated I-5111 Protein, IGUP I-5111, Proteasome Activator 28 Subunit alpha, PA28a, PA28alpha, IFI5111)

Size

£642.00

SKU:: P9075-75A
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Goat
Immunogen:: Synthetic peptide corresponding to C-KNFEKLKKPRGETK, from human PSME1, at C-terminal (NP_006254.1).
Format:: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Extra Details:: Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:64,000 Western Blot: 0.3-1ug/ml, observed in human lymph node, spleen, tonsil and peripheral blood mononuceocyte lysates on ~30kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.