Prostaglandin Dehydrogenase 1 (PGDH1, 15-Hydroxyprostaglandin Dehydrogenase [NAD+], Hydroxyprostaglandin Dehydrogenase 15-(NAD), HPGD, 15-PGDH, PGDH)

Size

£607.00

SKU:: P9053-27C1
Purity:: Purified by Protein A affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Purified type I human placental 15-PGDH protein.
Format:: Supplied as a liquid in Tris-glycine, 150mM sodium chloride, pH 7.2.
Extra Details:: 15-Hydroxyprostaglandin dehydrogenase (15-PGDH) is a novel tumor suppressor in the COX-2 pathway. The protein is found in many normal tissues and appears to be down-regulated in colorectal and lung carcinoma tissue. Applications: Suitable for use in Immunofluorescence, Western Blot and Immunohistochemistry (paraffin-embedded sections). Other applications not tested. Recommended Dilution: Western Blot: bands may be seen at 29kD and 58kD. Optimal dilutions to be determined by the researcher. Cellular Localization: Cytoplasmic Positive Control: Treated A549 lung carcinoma cell lysates (see note) and LoVo colon carcinoma cell lysates. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.