P9007-25A

Progesterone Receptor, unactive, Recombinant Human, aa1-160 (Prostaglandin E synthase 3, EC 5.3.99.3, Cytosolic prostaglandin E2 synthase, cPGES, Telomerase-binding protein p23, Hsp90 co-chaperone, Progesterone receptor complex p23)

Size

£576.00

SKU:: P9007-25A
Molecular Weight:: 18.6
Purity:: ~95% (SDS-PAGE) Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a liquid in 20 mM Tris-HCl, pH8.0, 1mM DTT 10% glycerol.
Extra Details:: Prostaglandin E synthase 3 (PTGES3), also known as P23 or TEBP (Telomerase binding protein p23), is a ubiquitously expressed protein that functions as a cochaperone and plays an important role in signal transduction. This protein is a molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Recombinant PTGES3 protein was expressed in E. coli and purified by using conventional chromatography techniques. Recombinant corresponding to aa1-160 from human PTGES3, expressed in E. coli. Amino Acid Sequence: MQPASAKWYD RRDYVFIEFC VEDSKDVNVN FEKSKLTFSC LGGSDNFKHL NEIDLFHCID PNDSKHKRTD RSILCCLRKG ESGQSWPRLT KERAKLNWLS VDFNNWKDWE DDSDEDMSNF DRFSEMMNNM GGDEDVDLPE VDGADDDSQD SDDEKMPDLE Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.