Presenilin 1, Loop, aa275-367 (Not for Export EU)

Size

£869.00

SKU:: P6300-20
Purity:: Serum
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Human Presenilin-1 (aa275–367) fused to C-terminus of maltose binding protein.
Format:: Supplied as a liquid in PBS, 0.01% sodium azide.
Extra Details:: The Presenilin-1 gene was recently discovered on chromosome 14 and is responsible for an early onset form of Alzheimer’s. It is a membrane protein that has a region where at least seven mutations have been identified in family members with Alzheimer’s disease (AD). The peptide corresponds to the C-terminus of this protein, which is exposed to the loop region. Applications: Suitable for use in Immunocytochemistry, Western Blot and Immunoprecipitation. Other applications have not been tested. Recommended Dilutions: Immunocytochemistry: Cos7, SY5Y cell lines. Western Blot: 1:500-1:3000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.