P5575-01B

PR Set7 (SET8, SET Domain Containing 8, SET Domain-containing Protein 8, SET Domain Containing Lysine Methyltransferase 8, SET Domain-containing (Lysine Methyltransferase) 8, SETD8, H4 K20 Specific Histone Methyltransferase, H4-K20-HMTase SETD8, PR/SET Domain-containing Protein 07, PrSET7, Pr-SET7, PR/SET07, PR/SET Domain-containing Protein 8, SET07)

Size

£927.00

SKU:: P5575-01B
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: GST-tagged recombinant protein corresponding to human SETD8 (hPR-SET7).
Format:: Supplied as a liquid in 0.1M Tris-glycine, pH 7.4, 0.15mM sodium chloride, 0.05% sodium azide.
Extra Details:: SETD8 (hPR-SET7) is a histone methyltransferase that adds a single methyl group to 'Lys-20' of histone H4. H4 'Lys-20' methylation represents a specific tag for epigenetic transcriptional repression. SETD8 (hPR-SET7) is located in the nucleus and may play a role in maintaining silent chromatin by preventing neighboring acetylation of H4 tail. Applications: Suitable for use in Western Blot and Immunocytochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Positive Control: HeLa nuclear extract. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.