P5575-01B-HRP

PR Set7 (SET8, SET Domain Containing 8, SET Domain-containing Protein 8, SET Domain Containing Lysine Methyltransferase 8, SET Domain-containing (Lysine Methyltransferase) 8, SETD8, H4 K20 Specific Histone Methyltransferase, H4-K20-HMTase SETD8, PR/SET Domain-containing Protein 07, PrSET7, Pr-SET7, PR/SET07, PR/SET Domain-containing Protein 8, SET07) (HRP)

Size

£1,183.00

SKU:: P5575-01B-HRP
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: GST-tagged recombinant protein corresponding to human SETD8 (hPR-SET7).
Format:: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with horseradish peroxidase (HRP).
Extra Details:: SETD8 (hPR-SET7) is a histone methyltransferase that adds a single methyl group to 'Lys-20' of histone H4. H4 'Lys-20' methylation represents a specific tag for epigenetic transcriptional repression. SETD8 (hPR-SET7) is located in the nucleus and may play a role in maintaining silent chromatin by preventing neighboring acetylation of H4 tail. Applications: Suitable for use in Western Blot and Immunocytochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Positive Control: HeLa nuclear extract. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.

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