P4448-31

POLE (Polymerase (DNA Directed), epsilon), DKFZp434F222, DNA Polymerase epsilon Catalytic Subunit A, DNA Polymerase II Subunit A, FLJ21434, POLE1)

Size

£685.00

SKU:: P4448-31
Purity:: Purified.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: POLE (AAH21559, 1-371aa) full-length human protein.
Format:: Supplied as a liquid in PBS, pH 7.2.
Extra Details:: POLE belongs to the DNA polymerase type-B family. It participates in DNA repair and in chromosomal DNA replication. The DNA polymerase activity domain resides in the N-terminal half of the protein, while the C-terminus is necessary for complexing subunits B and C. The C-terminus may also regulate the catalytic activities of the enzyme. POLE consists of two subunits, 258kD and 55kD. Applications: Suitable for use in Western Blot and Immunofluorescence. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.