P4271-14B
Plexin A2 (PLXNA2, Plex 2, Plexin-2, KIAA0463)
Size
£800.00
- SKU:
- P4271-14B
- Purity:
- Purified by Protein G affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rat
- Immunogen:
- Recombinant corresponding to mouse Plexin A2 expressed in CHO cells (P70207).
- Clone:
- 11D24
- Format:
- Supplied as a lyophilized powder in PBS, 5% trehalose. Reconstitute with 200ul sterile PBS.
- Extra Details:
- Plexin A2 (also OCT) is 220-230kD member of the Plexin A subfamily, Plexin family of proteins. It is found on cerebellar granule cells, sensory neurons, and cardiac neural crest cells. It participates in cell migration and axon guidance, and does so by serving as a receptor for Semaphorin 6A and B, and as a co-receptor with Neuropilin-1 for Semaphorin 3A and C. Mature mouse Plexin A2 is an 1860aa type I transmembrane glycoprotein. It contains a 1203aa extracellular domain (ECD) and a 636aa cytoplasmic region. The ECD contains one Sema-domain (aa40-481), three PSI domains (aa500-845) and four IPT regions (aa848-1226). There is one alternate start site 10 aa upstream of the standard start site. Over (aa25-1227), mouse Plexin A2 is 96% aa identical to human Plexin A2. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Direct ELISA: 0.5-1ug/ml Western Blot: 2ug/ml Optimal dilutions to be determined by the researcher. Hybridoma: Myeloma cells with B cells from Balb/c mice. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice