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P4262-20

Platensimycin

Size

£526.00

SKU:
P4262-20
Molecular Weight:
441.2
Purity:
≥ 95% by HPLC
Storage Conditions:
-20°C
Supplier:
United States Biological
CAS Number:
835876-32-9
Format:
Supplied as a white to buff solid.
Extra Details:
Platensimycin is a novel broad spectrum Gram-positive antibiotic produced by strains of Streptomyces platensis. Its discovery was heralded by high profile publication and commentary in the scientific and lay press. Platensimycin was discovered by target-based whole-cell screening strategy using an antisense differential sensitivity assay based on the inhibition of fatty acid synthesis. Platensimycin inhibits bacterial growth by selectively inhibiting the elongation enzyme, b-ketoacyl acyl carrier protein synthase FabF of the fatty acid synthesis pathway. Source: Platensimycin Molecular Weight: ~441.2 Solubility: Soluble in ethanol, methanol, DMF or DMSO. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with ethanol, methanol, DMF or DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Shipping Conditions:
Blue Ice