P4258-23R
PDGFRB, NT (Beta Platelet-derived Growth Factor Receptor, PDGF-R-beta, CD140 Antigen-like Family Member B, CD140b)
Size
£696.00
- SKU:
- P4258-23R
- Purity:
- Purified by ammonium sulfate precipitation.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 40-72 in the N-terminal region of human PDGFRB, UniProt Accession #P09619.
- Format:
- Supplied as a liquid in PBS, 0.09% sodium azide.
- Extra Details:
- PDGFRB is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. The gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses the gene to that of the translocation, ETS, leukemia gene, results in chronic myelomonocytic leukemia. Applications: Suitable for use in ELISA, Western Blot ,Indirect Flow Cytometry, Immunofluorescence and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 1:1000 Indirect Flow Cytometry: 1:10-1:50 Immunofluorescence: 1:10-1:50 Immunohistochemistry: (FFPE) 1:10-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice