P4230-01A

Plakophilin 1

Size

£825.00

SKU:: P4230-01A
Purity:: Supernatant
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Plakophilin 1 ("band 6 polypeptide" of bovine muzzle epidermis)
Clone:: PP1-5C2
Format:: Supplied as a liquid, 0.09% sodium azide.
Extra Details:: Desmosomes are adhesive intercellular junctions that act as cell surface attachment sites for intermediate filaments and play a role in providing strength to many tissues. In epithelial cells, the cytoplasmic side of desmosomes, the ‘desmosomal plaque’, represents a specific attachment structure for the anchorage of intermediate filaments (IF) of the cytokeratin type. Plakophilin-1 protein is one of several proteins that make up the desmosomal plaque, including plakoglobin and desmoplakin 1 and 2. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry (frozen): Undiluted-1:50 Immunohistochemistry (paraffin): Undiluted-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.