P4155

Piericidin A (Shaoguanmycin B, Antibiotic MT 1882-I, Antibiotic SN 198E, Antibiotic IT 143D, Piericidin A1)

Size

£368.00

SKU:: P4155
Molecular Weight:: 415.57
Purity:: ≥95% (HPLC)
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 2738-64-9
Format:: Pale yellow oil
Extra Details:: Piericidin A is the major analogue of a family of pyridyl antibiotics isolated from selected Streptomyces sp. It is a specific, potent inhibitor of NADH-ubiquinone oxidoreductase (Complex I) that binds to ubiquinone binding site(s). Piericidin A inhibits both mitochondrial and bacterial NADH-ubiquinone oxidoreductases, binding close to NUOD-NUOB interface. Source: Streptomyces sp. Synonyms: Shaoguanmycin B; Antibiotic MT 1882-I; Antibiotic SN 198E; Antibiotic IT 143D; Piericidin A1; 2-[(2E,4E,7E,9S,10S,11E)-10-hydroxy-3,7,9,11-tetramethyl-2,4,7,11-tridecatetraenyl]-5,6-dimethoxy-3-methyl-4-pyridinol CAS No: 2738-64-9 Molecular Formula: C25H37NO4 Molecular Weight: 415.57 Appearance: Pale yellow oil Purity: ≥95% (HPLC) Solubility: Ethanol, methanol, DMF or DMSO. Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.