P4072-06E
Phosphodiesterase 6 delta, Recombinant, Human (Phosphodiesterase 6D cGMP Specific Rod delta, PDE6 delta, PDE6D, PDED, GMP-PDE delta, Protein p17, Retinal Rod Rhodopsin Sensitive cGMP 3' 5' Cyclic Phosphodiesterase Subunit delta)
Size
£576.00
- SKU:
- P4072-06E
- Application:
- WB
- Molecular Weight:
- 18.4
- Purity:
- ~90% (SDS-PAGE). Purified by using conventional chromatography techniques.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Format:
- Supplied as a liquid in 20mM Tris HCl, pH 8.0, 1mM DTT, 100mM sodium chloride, 10% glycerol.
- Extra Details:
- Human PDE6D was originally identified as a fourth subunit of rod-specific cGMP phosphodiesterase, PDE6. Catalytically active PDE6 is a heterodimer (ab) that is regulated by two inhibitory γ subunits. As PDE6D does not modify the catalytic properties of PDEab, its function is still unresolved. Recombinant human PDE6D, fused to His-tag at C-terminus, was expressed in E. coli. Recombinant protein corresponding to aa1-150 of human PDE6D with a 6x His tagged expressed in E. coli (NP_002592). Amino Acid Sequence: MSAKDERARE ILRGFKLNWM NLRDAETGKI LWQGTEDLSV PGVEHEARVP KKILKCKAVS RELNFSSTEQ MEKFRLEQKV YFKGQCLEEW FFEFGFVIPN STNTWQSLIE AAPESQMMPA SVLTGNVIIE TKFFDDDLLV STSRVRLFYV GSHHHHHH Enzyme Activity: Not determined. This product is recommended for use in applications that do not require a catalytically active form of the protein. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice