P4070-87H

PHLPP, NT (PH Domain and Leucine Rich Repeat Protein Phosphatase 1, PH Domain Leucine-rich Repeat-containing Protein Phosphatase 1, PHLPP1, KIAA0606, MGC161555, Pleckstrin Homology Domain-containing Family E Member 1, PH Domain-containing Family E Member 1, PLEKHE1, Suprachiasmatic Nucleus Circadian Oscillatory Protein, SCN Circadian Oscillatory Protein, SCOP, hSCOP)

Size

£696.00

SKU:: P4070-87H
Purity:: Purified by ammonium sulfate precipitation.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide selected from the N-terminal region of human PHLPP1 (KLH).
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: PHLPP1 is a protein phosphatase that specifically mediates dephosphorylation of 'Ser-473' of AKT1, a protein that regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:50-1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.