Period Clock Protein 2 (Period 2, Period-2, Period 2 Isoform 1, Period Circadian Protein 2, Period Circadian Protein Homolog 2, Period Homolog 2, PER2, Circadian Clock Protein PERIOD2, Circadian Clock Protein PERIOD-2, FASPS, hPER2, KIAA0347)

Size

£594.00

SKU:: P3342-20D
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Partial synthetic peptide corresponding to an internal portion of the human PER2 protein (between amino acids 100-150). UniProt# O15055. Species Sequence Homology: Peptide 1 shows significant homology to rat (94.4%). Peptide 2 shows significant homology to rat and mouse (94.4%).
Format:: Supplied as a liquid in PBS, 0.02% sodium azide.
Extra Details:: PER2, a mammalian homolog of the Drosphilia period gene, shares 40% homology with PER1 including the protein dimerization PAS domain. A strong circadian rhythmic expression in the suprachiasmatic nuclei supports the view that the mammalian PER gene functions in the circadian clock with PER2 being a component of the circadian oscillator. Applications: Suitable for use in Western Blot, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry/Immunofluorescence. Other applications not tested. Recommended Dilutions: Western Blot: 1-2ug/ml Immunocytochemistry/Immunofluorescence: 1:100-1:500 Immunohistochemistry: 1:200 Immunohistochemistry (paraffin): 1:200 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice