P3270-01

Pepsin, 10,000+ U/mg (Porcine), NF/USP

Size

£192.00

SKU:: P3270-01
Molecular Weight:: 35
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 9001-75-6
Format:: White to slight yellow, powder.
Extra Details:: Pepsin, an acidic protease, is the principal proteolytic enzyme of vertebrate gastric juice. Its inactive precursor, pepsinogen, is produced in stomach mucosa. Pepsin has a broad range of substrates and demonstrates an esterase activity. There are several minor pepsins designated “B”, “C”, and “D”; the major component is “A” to which the following data applies. They are chromatographically separable. Conversion of pepsinogen to pepsin, which involves releasing a peptide, may be an autocatalytic process involving self-cleavage by the zymogen. Peptides released on activation have pepsin inhibitory activity. CAS No: 9001-75-6 Molecular Weight: ~35kD Source: Porcine stomach Appearance: White to slight yellow, powder Identification: Conforms Loss on Drying: ≤5% Protease Activity: ≥10,000U/mg [The activity of pepsin (10,000U/mg) is the same as strength (1:10,000NF).] Solubility: Soluble in Water. Mostly insoluble in alcohol Microbiology: Total Bacteria: ≤10,000cfu/g Yeast and Mold: ≤100cfu/g Bile-Tolerant Gram-Negative Bacteria: ≤100cfu/g E. coli: Negative/g S. aurues: Negative/g Salmonella: Negative/g Optimum pH: ~1.0 for such substrates as casein or hemoglobin if the substrate is native. Inhibitors: Substrate-like epoxides Storage and Stability: Powder may be stored at -20°C Stable for 6 months after receipt. Note: Meets or exceeds USP/NF Specifications

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