P3125-70H

PDRG1, aa1-133, Recombinant, Human (p53 and DNA-damage Regulated 1, C20orf126, PDRG)

Size

£607.00

SKU:: P3125-70H
Molecular Weight:: 17.6
Purity:: ~90% (SDS-PAGE).
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 0.2M sodium chloride, 5mM DTT, 20% glycerol.
Extra Details:: PDRG1, also known as PDRG or C20orf126, is a 133aa protein that localizes to the cytoplasm and belongs to the prefoldin subunit b family. Expressed predominately in normal testicular tissue, PDRG1 is functionally induced by ultraviolet light and is thought to play a role in chaperone-mediated protein folding, possibly playing a role in cellular degradation. It is associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Source: Recombinant corresponding to aa1-133 of human PDRG1 protein, fused to His-tag at N-terminus, expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MLSPEAERVL RYLVEVEELA EEVLADKRQI VDLDTKRNQN REGLRALQKD LSLSEDVMVC FGNMFIKMPH PETKEMIEKD QDHLDKEIEK LRKQLKVKVN RLFEAQGKPE LKGFNLNPLN QDELKALKVI LKG Molecular Weight: 17.6kD (153aa) confirmed by MALDI-TOF Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.