P3113-25A

PARP2 (Poly ADP-Ribose Polymerase 2, Poly (ADP-ribose) Polymerase Family Member 2, PARP-2, ADP Ribosyltransferase Like 2, ADPRT2, ADPRT-2, ADPRTL2, ADPRTL3, hPARP-2, NAD(+) ADP-ribosyltransferase 2, Poly (ADP-ribosyl) Transferase-like 2, pADPRT-2, Poly (ADP-ribose) Polymerase 2, Poly [ADP-ribose] Synthetase 2, Poly(ADP-ribose) Synthetase) (Not for Export EU)

Size

£659.00

SKU:: P3113-25A
Application:: WB
Purity:: Serum
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Residues 43-59 [QRQESKKMPVAGGKANK] of the 62kD human PARP-2 protein.
Format:: Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.
Extra Details:: Poly(ADP-ribose) polymerase 1, (PARP-1) and poly(ADP-ribose) polymerase 2 (PARP-2) catalyze the formation of poly(ADP-ribose) polymers in a DNA-dependent manner. PARP-2 displays automodification properties similar to PARP-1. These act by poly(ADP-ribosylation), which is a post-translational modification of nuclear proteins in response to DNA damage that activates the base excision repair machinery. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:250-1:500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.