P3112-04

Parkin (Ubiquitin-protein Ligase E3) (epitope a)

Size

£812.00

SKU:: P3112-04
Purity:: Purified by Protein G affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide (RILGEEQYNRYQQYGAEEC) corresponding to aa305-323 of human Parkin
Format:: Supplied as a liquid in PBS, pH 7.2.
Extra Details:: Parkin is a ubiquitin-protein ligase (E3) involved in the ubiquitin proteasomal pathway by participating in the removal of abnormally folded or damage protein. It is highly expressed in the brain, including the substancia nigra, and is also expressed in other tissues (heart, testis, skeletal muscle). Mutations in the parkin gene causing loss of E3 activity are responsible for autosomal recessive juvenile Parkinson's desease. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.