PARK 7 (DJ-1)

Size

£812.00

SKU:: P3110-99Q
Purity:: Purified by Protein G affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide (AAQVKAPLVLKD) corresponding to aa178-189 of human PARK 7
Format:: Supplied as a liquid in PBS, pH 7.2.
Extra Details:: PARK 7, also known as DJ-1 is a highly conserved cytoplasmatic protein and acts as a positive regulator of androgen receptor-dependent transcription. The expression of PARK 7 is induced by growth signals, and it is translocated from the cytoplasm to nucleous during S-phase of the cell cycle. PARK 7 also may fuction as redox-sensitive chaperone and as sensor for oxidative stress. Mutations in PARK 7 are associated with the autosomal recessive early-onset Parkinson's disease. Applications: Suitable for use in ELISA, Western Blot and Immunocytochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:1000 Western Blot: 1:1000 Immunocytochemistry: 1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.