p53 DINP1 (p53 Dependent Damage-inducible Nuclear Protein 1, p53 Damage-inducible Nuclear Protein 1, p53DINP1, DKFZp434M1317, FLJ22139, p53 Inducible Nuclear Protein 1, p53 Inducible p53DINP1, Stress Induced Protein, SIP, Teap, Tumor Protein p53 Inducible Nuclear Protein 1, TP53DINP1, TP53INP1, TP53INP1A, TP53INP1B) (MaxLight 490)

Size

£916.00

SKU:: P1001-31C5-ML490
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: 4°C Do Not Freeze
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to 14 amino acids, MFQRLNKMFVGEVS, near the N-terminus of human p53DINP1.
Format:: Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™490.
Extra Details:: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. p53DINP1 (p53-dependent damage-inducible nuclear protein 1). The protein promotes p53 phosphorylation on Ser46 in response to DNA double strand breaks, thereby inducing apoptosis. p53DINP1 is found in the nucleus and is ubiquitously expressed. Expression is dramatically reduced in pancreatic ductal adenocarcinomas early in the development of pancreatic cancer. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight™490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Shipping Conditions:: Blue Ice