p53 DINP1 (p53 Dependent Damage-inducible Nuclear Protein 1, p53 Damage-inducible Nuclear Protein 1, p53DINP1, DKFZp434M1317, FLJ22139, p53 Inducible Nuclear Protein 1, p53 Inducible p53DINP1, Stress Induced Protein, SIP, Teap, Tumor Protein p53 Inducible Nuclear Protein 1, TP53DINP1, TP53INP1, TP53INP1A, TP53INP1B) (Biotin)

Size

£916.00

SKU:: P1001-31C5-BIOTIN
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to 14 amino acids, MFQRLNKMFVGEVS, near the N-terminus of human p53DINP1.
Format:: Supplied as a liquid in PBS, pH 7.2. Labeled with Biotin.
Extra Details:: p53DINP1 (p53-dependent damage-inducible nuclear protein 1). The protein promotes p53 phosphorylation on Ser46 in response to DNA double strand breaks, thereby inducing apoptosis. p53DINP1 is found in the nucleus and is ubiquitously expressed. Expression is dramatically reduced in pancreatic ductal adenocarcinomas early in the development of pancreatic cancer. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.