Oxytocin Receptor (OTR, OT-R, OTR1, OXTR)

Size

£642.00

SKU:: O8251-04B
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Goat
Immunogen:: Syntehtic peptide corresponding to C-LRTTRQKHSRL at the internal region of human OXTR.
Format:: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Extra Details:: The oxytocin receptor, also known as OXTR, is a protein which functions as receptor for the hormone and neurotransmitter oxytocin. Oxytocin receptors are expressed by the myoepithelial cells of the mammary gland, and in both the myometrium and endometrium of the uterus at the end of pregnancy. The oxytocin-oxytocin receptor system plays an important role as an inducer of uterine contractions during parturition and of milk ejection. Oxytocin receptors are also present in the central nervous system. These receptors modulate a variety of behaviors, including stress and anxiety, social memory and recognition, sexual and aggressive behaviors, bonding (affiliation) and maternal behavior. In some mammals, oxytocin receptors are also found in the kidney and heart. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry and Flow Cytometry . Other applications not tested. Recommended Dilutions: ELISA (Peptide): 1:64,000 Western Blot: 2ug/ml Immunohistochemistry (Paraffin): 8ug/ml used human ovary Flow Cytometry: 1ug/ml using Jurkat cells Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice