Optineurin (FIP-2, NEMO-Related Protein, NRP)

Size

£704.00

SKU:: O7037
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to aa115-130 (KGKSERSSEDPTDDSR) of human optineurin (FIP-2 (14.7K interacting protein-2); NRP (nemo-related protein)).
Format:: Supplied as a liquid in TBS, pH 7.4, 0.02% sodium azide, 0.5mg/ml BSA, 50% glycerol.
Extra Details:: Optineurin (OPTN) has recently been linked to glaucoma, a major cause of blindness worldwide. Mutations in OPTN such as Glu50->Lys (E50K) have been reported in patients, particularly those with normal pressure glaucoma. Applications: Suitable for use in Immunohistochemistry and Western Blot. Other aapplications not tested. Recommended Dilutions: Immunohistochemistry: 10ug/ml (1hour incubation at RT). Overnight incubations at 4ºC with lesser IgG concentrations present good results. Western blot: 3ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.