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O7030-13

Opioid Receptor, delta, NT (Not for Export EU)

Size

£800.00

SKU:
O7030-13
Application:
IHC-Fr
Purity:
Serum
Storage Conditions:
-20°C
Supplier:
United States Biological
Host:
Rabbit
Immunogen:
Delta opioid receptor N-terminal peptide, LVPSARAELQSSPLV.
Format:
Supplied as a liquid. No preservative added.
Extra Details:
The function of the delta-opioid receptors has not been determined. However, recent studies in rodents have linked delta-opioid receptor antagonists with prevention of morphine tolerance and dependence without relinquishing mu-opioid antinociception. In general, opioids modulate numerous central and peripheral processes, including pain perception, neuroendocrine secretion and the immune response. The opioid signal is transduced from receptors through G proteins to various different effectors. Subsequent to G protein activation, several effectors are known to orchestrate the opioid signal. For example, activation of opioid receptors increases phosphatidylinositol turnover, activates K+ channels and reduces adenylyl cyclase and Ca++ channel activities. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry: 1:1000. CNS tissues fixed in PLP. Can be used with paraffin embedded tissue also. Optimal dilutions to be determined by the researcher. Positive Control: Spinal cord Control Peptide: O7030-12: Opioid Receptor, delta, NT, Control Peptide Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Shipping Conditions:
Blue Ice