NT-4,5 (Neurotrophin 4,5, NTF5)

Size

£639.00

SKU:: N6000-25C
Purity:: Purified by precipitation.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Chicken/Avian
Immunogen:: Human NT-4,5 mixed peptides
Format:: Supplied as a liquid.
Extra Details:: NT-4 Propeptide (neurotrophin-4/5) is a 27kD, secreted, glycosylated neuronal polypeptide that belongs to the NGF-b family of neurotrophic factors. It is synthesized as a proform that contains a 9kD, 56aa proregion (aa25-80) and a 130aa mature segment. The mature molecule forms both nondisulfide linked heterodimers (with NGF) and homodimers. It is unclear if 186aa NT-4 Propeptide dimerizes, but this might be anticipated. Proneurotrophins are believed to activate NGFR and sortilin complexes and neurotrophin proregions regulate neurotrophin maturation. Over aa25-80, human NT-4 Propeptide is 89% and 91% aa identical to mouse and canine NT-4 Propeptide, respectively. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Recommended Secondary Antibodies: I1906: IgY, Chicken Pab Rb xCh I1906-10: IgY, Chicken (HRP) Rb xCh I1906-12: IgY, Chicken (FITC) Rb xCh I1906-14: IgY, Chicken (AP) Rb xCh I1906-01: IgY, (HRP) Gt xCh Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice