N6000-07E
NT-3 (Neurotrophin 3, HDNF, NGF-2, Nerve growth factor-2)
Size
£895.00
- SKU:
- N6000-07E
- Purity:
- Purified by immunoaffinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- An 11 amino acid peptide corresponding to the amino-terminal of mouse Neurotrophin 3 (NT3) coupled to BSA.
- Format:
- Supplied as a lyophilized powder in PBS. No preservatives added. Reconstitute with sterile ddH2O to ~0.5-1mg/ml.
- Extra Details:
- NT-3 is a neurotrophic factor structurally related to NGF, BDNF, and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. NT-3 is expressed by neurons of the central nervous systems and can signal through the trk receptors. NT-3 promotes the growth and survival of nerve and glial cells. The amino acid sequences of human, murine and rat NT-3 are identical. Recombinant human NT-3 is a noncovalently linked homodimer, of two 13.6kD polypeptide monomers (238 total amino acid residues). Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 1-10ug/ml Immunohistochemistry: 1-10ug/ml Inhibition of biological activity in vitro: 1-10ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice