N5377-03P
Neutrophil Defensin 1, 3 (Defensin, alpha 1, HNP-1, HP-1, HP1, DEFA1, DEF1, DEFA2, MRS, DEFA1B/Defensin, alpha 3, HNP-3, HP-3, HP3, DEFA3, DEF3)
Size
£642.00
- SKU:
- N5377-03P
- Purity:
- Purified by immunoaffinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Goat
- Immunogen:
- Synthetic peptide corresponding to C-DESLAPKHPGSRKN, of human Neutrophil Defensin 1, 3 at the internal region of the protein.
- Format:
- Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
- Extra Details:
- Defensin alpha 1, otherwise known as HNP-1, is a secreted cationic antimicrobial peptide and member of the alpha-defensin family, which plays an important role in the innate immune response against microbial infections. Defensin 2 and defensin 3 have antibiotic, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. Applications: Suitable for use in ELISA, Immunohistochemistry and Western Blot. Other applications not tested. Recommended Dilutions: Peptide ELISA: 1:128,000 Western Blot: 1-3ug/ml ~10kD band observed in human spleen lysates Immunohistochemistry (Paraffin): 3-6ug/ml using human thymus. Requires HIER using sodium citrate buffer pH 6.0 prior to staining. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice