NO-Aspirin

Size

£403.00

SKU:: N2930-08
Molecular Weight:: 331.28
Purity:: ~90%
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 175033-36-0
Format:: Supplied as an off-white solid
Extra Details:: NO-Aspirin 1 is a hybrid molecule of aspirin and a nitric oxide (NO) donor. It contains an ester linkage, that when cleaved by esterases in the gut, liver, and plasma releases salicylate and an NO-releasing moiety. It also prevents restinosiis, inhibits proliferation of vascular smooth muscle cells, reduces infarct size following cardiac ischemia, and exhibits strong chemopreventative effects against colon cancer development. Melting Point: 59-64°C Solubility: Chloroform, Ethyl Acetate Method for Determining Identity: Proton NMR (CDCl3) Spectroscopic and Mass Spectrometric Analysis TLC conditions: SiO2; Hexane: Ethyl Acetate; 8:2; Visualizes with UV and AMCS; Single spot; Rf=0.35 Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20°C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap.