N2851-75P
NK1.1 Cell Surface Antigen (Killer Cell Lectin-like Receptor Subfamily B Member 1C, CD161 Antigen-like Family Member C, Lymphocyte Antigen 55c, Ly-55c, NKR-P1.9, NKR-P1C, Natural Killer Cell Surface Protein P1-40, NKR-P1 40, CD161c, Klrb1c, Ly55c, Nkrp1c)(APC)
Size
£466.00
- SKU:
- N2851-75P
- Purity:
- Purified
- Storage Conditions:
- 4°C Do Not Freeze
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- CD mouse spleen and bone marrow cells enriched for NK-1+ cells
- Clone:
- PK136
- Format:
- Supplied as a liquid in PBS, 0.09% sodium azide and a stabilizing agent. Labeled with APC.
- Extra Details:
- NK1.1, a member of the NKR-PI family of cell surface receptors, is a type II integral membrane protein with a C-type lectin domain. It is expressed as a disulfide-linked homodimer on all NK cells, as well as subsets of thymocytes and peripheral T lymphocytes in selected strains of mice (e.g., C57/BL6, FVB/N, NZB; but not A, AKR, BALB/c, CBA/J, C3H, C57BR, C58, DBA/1, DBA/2, SJL, 129).1-4 NK1.1 mediates cellular activation and differentiation, and is thought to have a particular role in generating Th2 cells.5-7 Applications: • Flow cytometry 1 • In vitro complement-dependent cytotoxicity assays 1 • Immunoprecipitation 8 • In vivo depletion and in vitro activation of NK1.1 cells 5,6 • In vitro redirected lysis 5 Recommended Dilution: Flow Cytometry: ≤ 0.5ug/10e6 cells Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice