N2851-75DX

NK1.1 Cell Surface Antigen (Killer Cell Lectin-like Receptor Subfamily B Member 1C, CD161 Antigen-like Family Member C, Lymphocyte Antigen 55c, Ly-55c, NKR-P1.9, NKR-P1C, Natural Killer Cell Surface Protein P1-40, NKR-P1 40, CD161c, Klrb1c, Ly55c, Nkrp1c) (Azide Free)

Size

£512.00

SKU:: N2851-75DX
Purity:: Purified
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: CD mouse spleen and bone marrow cells enriched for NK-1+ cells
Clone:: PK136
Format:: Supplied as a liquid in PBS. No preservative added.
Extra Details:: NK1.1, a member of the NKR-PI family of cell surface receptors, is a type II integral membrane protein with a C-type lectin domain. It is expressed as a disulfide-linked homodimer on all NK cells, as well as subsets of thymocytes and peripheral T lymphocytes in selected strains of mice (e.g., C57/BL6, FVB/N, NZB; but not A, AKR, BALB/c, CBA/J, C3H, C57BR, C58, DBA/1, DBA/2, SJL, 129).1-4 NK1.1 mediates cellular activation and differentiation, and is thought to have a particular role in generating Th2 cells.5-7 Applications: • Flow cytometry 1 • In vitro complement-dependent cytotoxicity assays 1 • Immunoprecipitation 8 • In vivo depletion and in vitro activation of NK1.1 cells 5,6 • In vitro redirected lysis 5 Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20°C or colder. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Shipping Conditions:: Blue Ice