NIBP (Trafficking Protein Particle Complex Subunit 9, NIK- and IKBKB-binding Protein, Tularik Gene 1 Protein, TRAPPC9, KIAA1882, T1) (Not for Export EU)

Size

£537.00

SKU:: N2497-65A
Purity:: Serum
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to aa282-299 (KKDFVGLDTDSRHYKKRC) of human NIBP.
Format:: Supplied as a liquid, 0.025% sodium azide, 50% glycerol.
Extra Details:: NIBP is a 1246aa intracellular regulatory protein. Reports suggest that NIBP physically interacts with NIK, IKK (beta), but not IKK (alpha) or IKK (gamma) and thus acts as a novel enhancer of cytokine-induced NF-(kappa) B signaling pathway. Due to its neuronal expression NIBP is considered as a potential target for modulating the NF-(kappa) B signaling cascade in neuronal pathologies dependent upon abnormal activation of this pathway. NIBP is mainly expressed in brain, muscle, heart, and kidney. Applications: Suitable for use in Immunofluorescence, Western Blot, Immunocytochemistry and Immunoprecipitation. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.