Nogo 66 Receptor (Ngr, Reticulon-4 Receptor, Nogo Receptor, Nogo-66 Receptor, RTN4R, NOGOR, UNQ330/PRO526)

Size

£642.00

SKU:: N2116-95P
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Goat
Immunogen:: Synthetic peptide corresponding to C-LQALPDDTFRDLGN, from human RTN4R, at the internal region of the protein (NP_075380.1).
Format:: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Extra Details:: NgR, also named reticulon 4 receptor, is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the family of leucine-rich repeat proteins. NgR plays an essential role in mediating axon growth inhibition induced by the myelin-derived proteins Nogo, myelinassociated glycoprotein (MAG), and myelin oligodendrocyte glycoprotein (Omgp). Upon ligand binding, NgR associates with and activates the p75 neurotrophin receptor (p75NTR), a tumor necrosis factor superfamily member (TNFRSF16). Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:16,000 Western Blot: 0.3-1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.