N2116-44A
Nogo-B Receptor (NgBR, Nuclear Undecaprenyl Pyrophosphate Synthase 1 Homolog, NUS1, C6orf68, NGBR)
Size
£594.00
- SKU:
- N2116-44A
- Application:
- WB
- Purity:
- Purified by Protein G affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide corresponding to aa64-74 (RNRRHHRHPRG) of human Nogo-B receptor (NgBR).
- Format:
- Supplied as a liquid in PBS, 0.05% BSA, 0.05% sodium azide.
- Extra Details:
- NgBR, also known as Nogo-B receptor, is a 293aa rich member of the UPP synthetase family. Though the exact function of NgBR is still not clear, reports suggest that this membrane protein acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator. It has similarity with UPP synthetase proteins which suggests that it may act as a scaffold for the binding of isoprenyl lipids and/or prenylated proteins but has no lipid transferase activity. NgBR colocalizes with Nogo-B during VEGF and wound healing angiogenesis and is thus able to regulate vascular remodeling and angiogenesis. Nogo-B and NgBR mediate chemotaxis in HUVECs and induced tube formation in three-dimensional cultures. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1-3ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Brain tissue lysate Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice