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N0520-25

Brain Natriuretic Peptide (BNP) (Not for Export EU)

Size

£435.00

SKU:
N0520-25
Purity:
Neat serum
Storage Conditions:
-20°C
Supplier:
United States Biological
Host:
Rabbit
Immunogen:
Synthetic peptide corresponding to human Brain Natriuretic Polypeptide covalently attached to bovine thyroglobulin.
Format:
Supplied as a lyophilized powder. No preservatives added. Reconstitute with 100ul sterile PBS, 10mg/ml BSA.
Extra Details:
Human brain natriuretic peptide (BNP) is a secreted protein which is a member of the natriuretic peptide family. BNP is a cardiac hormone, which is synthesised as a pro-hormone (proBNP), and is proteolytically cleaved to release a biologically active fragment (BNP), and an inactive fragment (NT-proBNP) into the circulation. BNP is predominantly secreted from the cardiac ventricles in response to volume and pressure overload, and results in a number of biological activities including natriuresis, diuresis, vasorelaxation, and inhibition of the sympathetic nervous system. A high concentration of BNP in the bloodstream is indicative of heart failure. Applications: Suitable for use in RIA, ELISA, Immunohistochemistry, Immunocytochemistry and Indirect Immunofluorescence. Other applications have not been tested. Recommended Dilutions: Immunohistochemistry: ≥1:1000. Stains rat brain sections using 3% paraformaldehyde and indirect immunofluorescent staining. Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with 100ul sterile PBS, 10mg/ml BSA. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Shipping Conditions:
Blue Ice