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N0019-65B

Natriuretic Peptide Receptor B, aa288-302 (NPR-B, ANPRB, GCB, Guanylate cyclase B, GUC2B, Natriuretic peptide receptor B/guanylate cyclase B, NPR2) (Not for Export EU)

Size

£358.00

SKU:
N0019-65B
Purity:
Serum
Storage Conditions:
-20°C
Supplier:
United States Biological
Host:
Rabbit
Immunogen:
Synthetic peptide corresponding to aa288-302, QNRLLIRAREDFGVE of human NPR-B, conjugated to poly-Lysine
Format:
Supplied as a lyophilized powder. Reconstitute with 20ul or 100ul sterile ddH2O.
Extra Details:
ANPB (natriuretic peptide receptor B) is one of two integral membrane receptors for natriuretic peptides. Both ANPA and ANPB contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain), an helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. ANPB is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Applications: Suitable for use in Western Blot and Immunocytochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 1:1500-1:10,000 Immunocytochemistry: 1:200-400 Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Shipping Conditions:
Blue Ice