NR4A1, ID (Nuclear Receptor Subfamily 4 Group A Member 1, Orphan Nuclear Receptor TR3, Orphan Nuclear Receptor HMR, Early Response Protein NAK1, Testicular Receptor 3, ST-59, Nur77, GFRP1, HMR, NAK1)

Size

£642.00

SKU:: N0018-01J
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Goat
Immunogen:: Synthetic peptide corresponding to C-GRLPSKPKQPPDAS from an internal region of human NR4A1. Species Sequence Homology: canine, elephant, equine, gibbon, gorilla, hamster, orangutan, panda, monkey, mouse, rabbit, rat (100%); bat, marmoset (93%); bovine (86%)
Format:: Supplied as a liquid in TBS, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Extra Details:: NR4A1 is a member of the steroid-thyroid hormone-retinoid receptor superfamily. Expression is induced by phytohemagglutinin in human lymphocytes and by serum stimulation of arrested fibroblasts. This protein acts as a nuclear transcription factor. Translocation of the protein from the nucleus to mitochondria induces apoptosis. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: ELISA: 1:32,000 Western Blot: 1-3ug/ml Immunohistochemistry (FFPE): 5ug/ml; Heat induced antigen retrieval in citrate buffer, pH 6.0. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.