N0017-05

NAGLU (Alpha-N-acetylglucosaminidase, N-acetyl-alpha-glucosaminidase, NAG, UFHSD1) (Azide Free)

Size

£685.00

SKU:: N0017-05
Application:: WB
Purity:: Purified
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Partial recombinant protein corresponding to a portion of corresponding to a portion of amino acids within aa644-743 from human NAGLU, with GST tag. MW of GST tag alone is 26kD (NP_000254)
Clone:: 11C455
Format:: Supplied as a liquid in PBS, pH 7.2. No preservative added (Azide free).
Extra Details:: This gene encodes an enzyme that degrades heparan sulfate by hydrolysis of terminal N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. Defects in this gene are the cause of mucopolysaccharidosis type IIIB (MPS-IIIB), also known as Sanfilippo syndrome B. This disease is characterized by the lysosomal accumulation and urinary excretion of heparan sulfate. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 1:500-1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.