Myosin X (Myosin heavy chain 10, Cellular myosin heavy chain, type B, Myosin-10, Myosin heavy chain, non-muscle IIb, NMMHCB, NMMHC-B, NMMHC II-b, NMMHC-IIB, Non-muscle myosin heavy chain B, Non-muscle myosin heavy chain IIb) (Not for Export EU)

Size

£819.00

SKU:: M9850-75A
Application:: WB
Purity:: Serum
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to aa936-953 of human Myosin X (KLH).
Format:: Supplied as a liquid, 0.05% sodium azide.
Extra Details:: Myosins are a superfamily of molecular motor proteins found in eukaryotic cells. Motor proteins are involved in muscular contraction, cytokinesis, short-range membrane/vesicle transport and a host of other cellular processes. The myosins are responsible for actin-based motility by using the energy of ATP hydrolysis to generate force and movement along actin filaments. There are many isoforms of myosin of which some have specialized functions in certain cell types (such as muscle), while other isoforms are ubiquitous. Myosin X belongs to a group of myosin isoforms known as unconventional myosins that participate in cellular processes ranging from membrane trafficking to signaling and cell motility. Myosin X is concentrated at the tips of filopodia and Myosin X rich regions travel forward and backward along filopods, (Berg, 2002). It also appears that Myosin X functions in actual filopodia formation, (Bohil, 2006). Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:2000 Optimal dilutions to be determined by the researcher. Positive Control: Human head/neck lysate. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice