M9520-21
Muscarinic Receptor M3, aa580-589 (Cholinergic Muscarinic Receptor M3, Chrm3)
Size
£700.00
- SKU:
- M9520-21
- Purity:
- Purified by precipitation, dialysis and chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- A peptide analogue of the carboxyl terminal of the M3 receptor covalently attached to a carrier protein
- Format:
- Supplied as a liquid in PBS, 10mg/ml BSA.
- Extra Details:
- The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and stimulates secretion in glandular tissue. Applications: Suitable for use in ELISA, Immunohistochemistry and Western Blot. Other applications have not been tested. Recommended Dilutions: Immunohistochemistry: 10ug/ml stains rat brain sections that express the muscarinic M3 receptor after fixing with PLP fixative and using ABC techniques. Western Blot: 50ug/ml stains whole rat brain homogenates. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice