M9515-01B

Musashi-1 RNA Binding Protein, Control Peptide (Mi, Msi-1) (BSA)

Size

£269.00

SKU:: M9515-01B
Purity:: Purified
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a liquid in MES pH5. Conjugated to BSA.
Extra Details:: Control peptide for M9515-01 which recognizes Musashi RNA Binding Protein in human and rodent. Musashi1, a neural RNA-binding protein, plays an important role in regulating cell differentiation in precursor cells. Musashi-1 (Msi-1) has been shown to increase the accumulation of tau isoforms in intracellular inclusions in dementia and Parkinson's. The presence of Msi-1 in a significant percentage of neurons containing cytoplasmic inclusions in 2 other neurodegenerative diseases Alzheimer's disease and Pick disease suggests that it may play a role in the pathogenesis of these neurodegenerative disorders. Musashi1 has also been detected in human tumor tissues such as gliomas and melanomas, suggesting its involvement in cancer development. Msi-1 also appears to play a vital role in the development of several types of carcinoma such as human hepatoma and may be a useful molecular marker for tumor detection. Applications: Suitable for use in ELISA, Western Blotting. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher.