MUCDHL (Cadherin-related Family Member 5, Mu-protocadherin, Mucin and Cadherin-like Protein, CDHR5, MUPCDH, UNQ2781/PRO7168)

Size

£448.00

SKU:: M4703-11A
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Goat
Immunogen:: Synthetic peptide corresponding to C-PYDAPGGDDSY, from MUPCDH, at C-terminal (NP_068743.2, NP_112554.2).
Format:: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Extra Details:: Mucin and cadherin-like protein (MUCDHL), also known as mu-protocadherin, is a 110kD type I transmembrane protein that is both O- and N-glycosylated. It is a calcium-dependant cell adhesion protein in the cadherin superfamily. MUCDHL is found on intestinal and renal epithelium. Human MUCDHL extracellular domain (ECD) contains four cadherin domains (aa71-459) plus several mucin domains (aa540-645). Alternate splicing creates four isoforms that differ in their mucin domains. In the region used as immunogen, human and mouse MUCDHL share 63% aa sequence identity. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:8000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.