M4701-15
Mucin 5B (MUC5B)
Size
£787.00
- SKU:
- M4701-15
- Purity:
- Purified by Protein A affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Synthetic peptide derived from the N-terminal region of the human MUC5B protein.
- Clone:
- 4H310
- Format:
- Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
- Extra Details:
- Mucins (MUCs) are heavily glycosylated glycoproteins that are synthesized either as membrane-bound or secreted proteins. Mucins are noteworthy because they have an aberrant expression profile in various malignancies. Mucins normally play a protective role for epithelial tissues. They are expressed in the gastrointestinal, respiratory and genito-urinary tracts. Mucins may be involved in the renewal and differentiation of the epithelium, and the modulation of cell adhesion and cell signaling. MUC5B is thought to play a vital role in maintaining oral health, and may be involved in respiratory and oral disease. MUC5B expression has been studied in gastric carcinoma as well as chronic obstructive pulmonary disease. Applications: Suitable for use in ELISA, Immunohistochemistry, Western Blot and Immunofluorescence/Immunocytochemistry. Other applications not tested. Recommended Dilutions: Immuofluorescence (IC): 2ug/ml Optimal dilutions to be determined by the researcher. Source: Ascites Storage and Stability:: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice