M4688-39A
MRP9 (Multidrug Resistance-associated Protein 9, ATP-binding Cassette Sub-family C Member 12, ABCC12, MGC27071)
Size
£709.00
- SKU:
- M4688-39A
- Purity:
- Supernatant
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rat
- Immunogen:
- Bacterial fusion protein corresponding to aa690-734 of human MRP9.
- Clone:
- M9II-3
- Format:
- Supplied as a liquid in 0.7% BSA, 0.09% sodium azide.
- Extra Details:
- Multidrug resistance-associated protein 9 is a protein that in humans is encoded by the ABCC12 gene. This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. Applications: Suitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 1:20-1:50 Immunohistochemistry (Acetone fixed frozen): 1:20, followed by incubation with RbxRt IgG and a monoclonal rat APAAP complex. Alternatively after incubation with M4688-39A and washing, slides can be incubated with RbxRt IgG (Biotin) and streptavidin conjugated to HRP. Immunocytochemistry: 1:20-1:50 on acetone fixed cytospin preparations. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice