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M4688-39

MRP9 (Multidrug Resistance-associated Protein 9, ATP-binding Cassette Sub-family C Member 12, ABCC12, MGC27071)

Size

£709.00

SKU:
M4688-39
Purity:
Supernatant
Storage Conditions:
-20°C
Supplier:
United States Biological
Host:
Rat
Immunogen:
Bacterial fusion protein corresponding to aa1-42 from human MRP9.
Clone:
M9I-38
Format:
Supplied as a liquid in 0.7% BSA, 0.09% sodium azide.
Extra Details:
Multidrug resistance-associated protein 9 is a protein that in humans is encoded by the ABCC12 gene. This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 1:20-1:50 Immunohistochemistry (Acetone fixed frozen): 1:20-1:50 Immunocytochemistry (Acetone fixed cytospin): 1:20-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Shipping Conditions:
Blue Ice